Geomicrobiologist Felisa Wolfe-Simon, collecting lake-bottom sediments in the shallow waters of Mono Lake in California. Wolfe-Simon cultured the arsenic-utilizing organisms from this hypersaline and highly alkaline environment. Credit: ©2010 Henry Bortman
One of the basic assumptions about life on Earth may be due for a revision thanks to research supported by NASA’s Astrobiology Program. Geomicrobiologist Felisa Wolfe-Simon has discovered a bacterium in California’s Mono Lake that uses arsenic instead of phosphorus in its DNA. Up until now, it was believed that all life required phosphorus as a fundamental piece of the ‘backbone’ that holds DNA together. The discovery of an organism that thrives on otherwise poisonous arsenic broadens our thinking about the possibility of life on other planets, and begs a rewrite of biology textbooks by changing our understanding of how life is formed from its most basic elemental building blocks. Astrobiology Magazine has the story.
Wolfe-Simon’s research is supported by NASA’s Exobiology and Evolutionary Biology (Exo/Evo) Program and the NASA Astrobiology Institute. Among the goals of these programs is determining the evolution of genes, metabolic pathways, and microbial species on Earth in order to understand the potential for life on other worlds. Wolfe-Simon’s discovery represents the first time in the history of biology that an organism has been found to use a different element to build one of its most basic structures. The paper appears in today’s issue of “Science Express“ and will subsequently be published in the journal Science.
砷终于代替了磷……这样，生命就不再是我们所说的生命了。很早以前就想也许外星生命并不像我们想的那样，那么遥远，那么神秘。也许它很微小，就在这地球上。现在，DNA中的磷都能被代替，那还有什么不可能的呢？
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